This new chapter in The Spider-Man legacy focuses on an untold story that tells a different side of Peter Parker's story. He was abandoned by his parents as a boy, and raised by his Uncle Ben and Aunt May. As a teenager, Peter is finding out who he is, and how he has become the person he is today. As Peter discovers a mysterious briefcase that belonged to his father, he begins a quest regarding his parents' disappearance. This leads him directly to Oscorp and the lab of Dr. Curt Connors, his father's, partner. As Spider-man is set on a collision course with Connor's alter-ego, The Lizard, Peter will make life-altering decisions to use his powers and shape his destiny to become a hero.